Journal Title：Virchows Archiv

Manuscripts of original studies reinforcing the evidence base of modern diagnostic pathology, using immunocytochemical, molecular and ultrastructural techniques, will be welcomed. In addition, papers on critical evaluation of diagnostic criteria but also broadsheets and guidelines with a solid evidence base will be considered. Consideration will also be given to reports of work in other fields relevant to the understanding of human pathology as well as manuscripts on the application of new methods and techniques in pathology. Submission of purely experimental articles is discouraged but manuscripts on experimental work applicable to diagnostic pathology are welcomed. Biomarker studies are welcomed but need to abide by strict rules (e.g. REMARK) of adequate sample size and relevant marker choice. Single marker studies on limited patient series without validated application will as a rule not be considered. Case reports will only be considered when they provide substantial new information with an impact on understanding disease or diagnostic practice.

欢迎使用免疫细胞化学、分子和超微结构技术加强现代诊断病理学证据基础的原创研究手稿。此外，还将考虑对诊断标准进行批判性评估的论文，以及具有坚实证据基础的大报和指南。还将考虑与理解人类病理学相关的其他领域的工作报告以及关于在病理学中应用新方法和技术的手稿。不鼓励提交纯粹的实验文章，但欢迎提交适用于诊断病理学的实验工作的手稿。生物标志物研究受到欢迎，但需要遵守足够样本量和相关标志物选择的严格规则（例如 REMARK）。没有经过验证的应用的有限患者系列的单一标志物研究通常不予考虑。只有当病例报告提供了对理解疾病或诊断实践有影响的大量新信息时，才会考虑病例报告。